Abstract Background The performance of 3D-based virtual screening similarity functions is affected by the applied conformations of compounds.Therefore, here the results of 3D approaches are often less robust than 2D approaches.The application of 3D methods on multiple conformer data sets normally reduces this weakness, but entails a significant com
Psychosocial intervention trials for youth at clinical high risk (CHR) for psychosis have shown promising effects on treating psychotic symptoms but have not focused on psychosocial functional outcomes, and those studies have been conducted among help-seeking patients; there is a lack of research on non-clinical young CHR individuals.Systemic thera
Abstract The emerging bushranger awning risks facing humanity have highlighted the need to address and prevent challenges through multilateral preventive strategies.The Mexico-United States (US) border is a region with great biological biodiversity and both countries shared a similar history and intense socioeconomic, and cultural interrelationship
ABSTRACT: Among Italian dairy cattle, the Holstein is the most reared breed for the production of Parmigiano Reggiano protected designation of origin cheese, which represents one of the most renowned products in the entire Italian dairy industry.In this work, we used a medium-density genome-wide data set consisting of 79,464 imputed SNPs to study t
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